FCGR3 Protein (C-His, Rhesus)

Product Specifications

Abbreviation

FCGR3

Host

HEK 293

Tag

C-His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 95 % as determined by SDS-PAGE

Bioactivity

1.Loaded Recombinant Rhesus CD16/FCGR3/Fc gamma RIII Protein, His Tag (Cat. No. 90013-C08H) on NTA Biosensor, can bind Rituximab derived Anti-CD20 (Ro) Antibody, Human IgG1 with an affinity constant of 0.412 μM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested) . 2.Recombinant Rhesus CD16/FCGR3/Fc gamma RIII Protein, His Tag (Cat. No. 90013-C08H) captured on CM5 chip via Anti-his antibody, can bind Rituximab derived Anti-CD20 antibody, Human IgG1 with an affinity constant of 0.226 μM as determined in an SPR assay (Biacore 8K) (QC tested) .

Function

Met1-Gly206

Molecular Weight

The recombinant rhesus CD16 consists of 201 amino acids and has a calculated molecular mass of 22.7 kDa.

Species

Rhesus