ENG Protein (C-human IgG1-Fc, Human)

Product Specifications

Abbreviation

ENG

Synonyms

CD105, END, HHT1, ORW1

Host

HEK 293

Tag

C-human IgG1-Fc

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

≥ 95 % as determined by SDS-PAGE. ≥ 85 % as determined by SEC-HPLC.

Bioactivity

1. Measured by its ability to bind biotinylated Human TGFRB1 in a functional ELISA. 2. Measured by its ability to bind biotinylated Human ALK1-Fc (Cat:10066-H02H) in functional Elisa.

Function

Met1-Gly586

Molecular Weight

The recombinant human CD105/Fc chimera is a disulfide-linked homodimeric protein. The reduced monomer consists of 799 amino acids and has a predicted molecular mass of 87.5 kDa. As a result of glycosylation, rhCD105/Fc monomer migrates as an approximately 115-120 kDa protein in SDS-PAGE under reducing conditions.