Acid-PEG3-C2-Boc

Acid-PEG3-C2-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs for the degradation of EGFR and inhibition of mTOR[1][2].

Product Specifications

CAS Number

[1807539-06-5]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/acid-peg3-c2-boc.html

Purity

99.90

Solubility

DMSO : 175 mg/mL

Smiles

CC(C)(C)OC(CCOCCOCCOCCC(O)=O)=O

Molecular Formula

C14H26O7

Molecular Weight

306.35

Precautions

H302, H315, H319, H335

References & Citations

[1]Nathanael Gray, et al. Bifunctional molecules for degradation of egfr and methods of use. WO2017185036A1.|[2]Christopher Semko, et al. Rapamycin analogs as mtor inhibitors. WO 2018204416 A1.