Acid-PEG3-C2-Boc
Acid-PEG3-C2-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs for the degradation of EGFR and inhibition of mTOR[1][2].
Product Specifications
CAS Number
[1807539-06-5]
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/acid-peg3-c2-boc.html
Purity
99.90
Solubility
DMSO : 175 mg/mL
Smiles
CC(C)(C)OC(CCOCCOCCOCCC(O)=O)=O
Molecular Formula
C14H26O7
Molecular Weight
306.35
Precautions
H302, H315, H319, H335
References & Citations
[1]Nathanael Gray, et al. Bifunctional molecules for degradation of egfr and methods of use. WO2017185036A1.|[2]Christopher Semko, et al. Rapamycin analogs as mtor inhibitors. WO 2018204416 A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Alkyl/ether Linkers; PEG Linkers
Available Sizes
Curated Selection
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