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CTLA4 Protein (C-His-AVI, Mouse)

Product Specifications

Abbreviation

CTLA4

Synonyms

Cd152, Ctla-4, Ctla4, Ly-56

Host

HEK 293

Tag

C-His-AVI

Endotoxin

< 1.0 EU per μg protein as determined by the LAL method.

Purity

≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.

Bioactivity

1.Immobilized Recombinant Mouse CD80 / B7-1 Protein (Fc Tag) (Cat: 50446-M02H) at 2 μg/mL (100 μL/well) can bind Recombinant Mouse CTLA-4 Protein (His & AVI Tag), Biotinylated (Cat: 50503-M49H-B), the EC50 is 7-21 ng/mL (Routinely tested) . 2.Immobilized Recombinant Mouse CTLA-4 Protein (His & AVI Tag), Biotinylated (Cat: 50503-M49H-B) at 1 μg/mL (100 μl/well) on streptavidin precoated (5 μg/mL, 100 μL/well) can bind Anti-CTLA4 (Research grade Ipilimumab biosimilar), the EC50 is 15-45 ng/mL (QC tested) .

Function

Met1-Phe162

Molecular Weight

The recombinant Mouse CTLA4 consists of 153 amino acids and predicts a molecular mass of 17.27 kDa. It migrates as an approximately 30.4 kDa band in SDS-PAGE under reducing conditions.

Species

Mouse

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