Trastuzumab Deruxtecan Biosimilar - Research Grade
Product Specifications
Background
Trastuzumab deruxtecan is a HER2-targeting ADC structurally composed of a humanized anti-HER2 antibody, enzymatically cleavable peptide-linker, and a novel topoisomerase I inhibitor (DXd), which is cell-membrane permeable and more potent than SN-38 the active metabolite of irinotecan.
Product Name Alternative
Dxd
Host
CHO Cells
Reactivity
Human
Target
ERBB2 / HER2 / CD340
Isotype
IgG1
Applications
Functional Assays
Concentration
1mg/mL
Purity
>90% by SDS-PAGE
Shipping Conditions
Room Temp
Storage Conditions
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Formulation
25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)
Applications Notes
Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.
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