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Recombinant Myosin Light Chain 3 Monoclonal Antibody

Product Specifications

Background

MYL3, also named as MLC1v, is an essential light chain of myosin that is associated with muscle contraction. It is expressed in ventricular and slow skeletal muscle. MYL3 may serve as a target for caspase-3 in dying cardiomyocytes. Mutations of MYL3 gene cause hypertrophic cardiomyopathy. MYL3 has been identified as potential serum biomarker for drug induced myotoxicity. Great increase in MYL3 serum concentration has been observed in rats with cardiac and skeletal muscle injury.

Abbreviation

Myosin Light Chain 3

UniProt

P08590

Host

Rabbit

Reactivity

Human; Rat; Mouse

Immunogen

Recombinant human Myosin Light Chain 3 fragment

Target

Myl; MYL3; alkali; Cardiac myosin light chain 1; CMH8; CMLC1; ELC of myosin; Essential light chain of myosin; light chain 1; light chain 3; light polypeptide 3; MLC1SB; MLC1V; Myosin; Myosin light chain 1; Myosin light chain 1 slow; Myosin light chain 1 slow twitch muscle B/ventricular isoform; Myosin light chain 3; OTTHUMP00000165922; skeletal; slow; Slow skeletal ventricular myosin alkali light chain 3; slow-twitch muscle B/ventricular isoform; ventricular; Ventricular/slow twitch myosin alkali light chain; VLC1

Clonality

Monoclonal,Recombinant

Clone

A310

Conjugation

Unconjugated

Applications

WB; IHC; FCM

Field of Research

Signal Transduction; Cardiovascular

Purification

Protein A purified

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:200-1:1000; FCM 1:50-1:100

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

22 kDa

Observed Molecular Weight

22 kDa

Isotype

IgG, κ

Available Sizes

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