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Anti-CLEC4E Antibody (Monoclonal, ABM42E6)

Boster Bio Anti-CLEC4E Antibody (Monoclonal, ABM42E6) (Catalog# M06084) . Tested in FACS, WB application (s) . This antibody reacts with Human.

Product Specifications

Synonyms

C-type lectin domain family 4 member E; C-type lectin superfamily member 9; Macrophage-inducible C-type lectin; CLEC4E; CLECSF9, MINCLE; UNQ218/PRO244

Gene Name

CLEC4E

UniProt

Q9ULY5

Host

Mouse

Reactivity

Human

Immunogen

A full length human CLEC4E protein

Clonality

Monoclonal

Clone

Clone: ABM42C6

Applications

FACS, WB

Field of Research

Immunology, Innate Immunity, Macrophage/Inflammation

Purification

Protein G Chromatography

Concentration

0.5-1mg/mL, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

C-type lectin that functions as cell-surface receptor for a wide variety of ligands such as damaged cells, fungi and mycobacteria. Plays a role in the recognition of pathogenic fungi, such as Candida albicans. The detection of mycobacteria is via trehalose 6,6'-dimycolate (TDM), a cell wall glycolipid. Specifically recognizes alpha-mannose residues on pathogenic fungi of the genus Malassezia. Recognizes also SAP130, a nuclear protein, that is released by dead or dying cells. Transduces signals through an ITAM-containing adapter protein, Fc receptor gamma chain /FCER1G. Induces secretion of inflammatory cytokines through a pathway that depends on SYK, CARD9 and NF-kappa-B. .

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Observed Molecular Weight

25073 MW

Gene Name Synonym

C-type lectin domain family 4 member E

Subcellular Location

Membrane; Single-pass type II membrane protein.

Protein Name

C-type lectin domain family 4 member E

Isotype

IgG1 Kappa

Contents

100 μ g in 200 μ l PBS containing 0.05% BSA and 0.05% sodium azide.

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