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Anti-ATP2A3 Antibody (N-Term)

Boster Bio Anti-ATP2A3 Antibody (N-Term) (Catalog # M04597) . Tested in WB, IHC-P application (s) . This antibody reacts with Human.

Product Specifications

Background

This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. Transports calcium ions from the cytosol into the sarcoplasmic/endoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction.

Synonyms

Sarcoplasmic/endoplasmic reticulum calcium ATPase 3, SERCA3, SR Ca (2+) -ATPase 3, Calcium pump 3, ATP2A3

Gene Name

ATP2A3

UniProt

Q93084

Host

Rabbit

Reactivity

Human

Immunogen

This ATP2A3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 13-47 amino acids from human ATP2A3.

Clonality

Polyclonal

Tissue Specificity

Found in most tissues. Most abundant in thymus, trachea, salivary gland, spleen, bone marrow, lymph node, peripheral leukocytes, pancreas and colon. Also detected in fetal tissues Expressed in cell lineages of hematopoietic, epithelial, or embryonic origin and also expressed in several cancer cell lines

Applications

WB, IHC-P

Field of Research

Metabolism, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. Transports calcium ions from the cytosol into the sarcoplasmic/endoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

109256 Da

Subcellular Location

Nucleus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Sarcoplasmic reticulum membrane; Multi-pass membrane protein

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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