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Phospho-IKBA (Ser32/36) antibody

Product Specifications

Background

This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.

Synonyms

NF-kappa-B inhibitor alpha|I-kappa-B-alpha (IkB-alpha, IkappaBalpha) |Major histocompatibility complex enhancer-binding protein MAD3|NFKBIA|IKBA|MAD3|NFKBI

Gene ID

4792

UniProt

P25963

Host

Rabbit

Reactivity

Human

Immunogen

Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha

Target

Phospho-IKBA (Ser32/36)

Clonality

Polyclonal

Isotype

IgG

Applications

WB

Purification

Immunogen affinity purified

Dilution

WB: 1:1000-1:10000

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

39 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

WB

Immunogen Sequence

Peptide

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