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Anti-PBRM1 Antibody

Boster Bio Anti-PBRM1 Antibody (Catalog # M01130-2) . Tested in WB application (s) . This antibody reacts with Human.

Product Specifications

Background

Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology) . Acts as a negative regulator of cell proliferation.

Synonyms

Protein polybromo-1, hPB1, BRG1-associated factor 180, BAF180, Polybromo-1D, PBRM1, BAF180, PB1

Gene Name

PBRM1

UniProt

Q86U86

Host

Mouse

Reactivity

Human

Immunogen

This PBRM1 antibody is generated from a mouse immunized with a recombinant proteinof human PBRM1.

Clonality

Monoclonal

Clone

Clone: 1636CT387.122.52

Tissue Specificity

Widely expressed.

Applications

WB

Purification

This antibody is purified through a protein G column, followed by dialysis against PBS.

Function

Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology) . Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF) . Acts as a negative regulator of cell proliferation.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

192948 Da

Applications Notes

WB: 1:1000

Subcellular Location

Nucleus

Isotype

IgG1, k

Contents

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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