Anti-RILP-like protein 1 RILPL1 Antibody
Boster Bio Anti-RILP-like protein 1 RILPL1 Antibody (Catalog # A13355) . Tested in ELISA, WB, IF applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Background
While the function of the Rab interacting lysosomal protein-like 1 (RILPL1) remains unknown, the homologous protein RILP is a small GTPase that controls transport to endocytic compartments, suggesting RILPL1 may have similar functions. However, overexpression of RILP caused enlarged lysosomes that are more centrally located in the cell, while overexpression of RILPL1 had no visible effect on the location or morphology of lysosomes.
Synonyms
RLP1, GOSPEL, RLP1, RILP-like protein 1, Rab-interacting lysosomal-like protein 1
Gene Name
RILPL1
UniProt
Q5EBL4
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
At least three isoforms of RILPL1 are known to exist; this antibody will detect the two shorter isoforms. RILPL1 antibody is predicted to not cross-react with RILP.
Immunogen
RILPL1 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human RILPL1. The immunogen is located within the last 50 amino acids of RILPL1.
Clonality
Polyclonal
Tissue Specificity
Widely expressed. Expressed at lower level in liver and kidney.
Applications
ELISA, WB, IF
Field of Research
Homeostasis
Purification
RILPL1 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL
Form
Liquid
Function
Plays a role in the regulation of cell shape and polarity. Plays a role in cellular protein transport, including protein transport away from primary cilia. Neuroprotective protein, which acts by sequestring GAPDH in the cytosol and prevent the apoptotic function of GAPDH in the nucleus. Competes with SIAH1 for binding GAPDH (By similarity) . Does not regulate lysosomal morphology and distribution. .
Storage Conditions
RILPL1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Observed Molecular Weight
47108 MW
Gene Name Synonym
Rab interacting lysosomal protein-like 1
Subcellular Location
Cytoplasm, cytosol
Prediction Reactivity
Bovine
Protein Name
Rab interacting lysosomal protein-like 1
Isotype
IgG
Contents
RILPL1 Antibody is supplied in PBS containing 0.02% sodium azide.
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