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Anti-IDH3B Antibody (N-term)

Boster Bio Anti-IDH3B Antibody (N-term) (Catalog # A09433-2) . Tested in IHC-P, WB application (s) . This antibody reacts with Human.

Product Specifications

Synonyms

Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial, Isocitric dehydrogenase subunit beta, NAD (+) -specific ICDH subunit beta, IDH3B

Gene Name

IDH3B

UniProt

O43837

Host

Rabbit

Reactivity

Human

Immunogen

This IDH3B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 15-49 amino acids from the N-terminal region of human IDH3B.

Clonality

Polyclonal

Applications

IHC-P, WB

Field of Research

Metabolism, Signal Transduction, Mitochondria

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Plays a structural role to facilitate the assembly and ensure the full activity of the enzyme catalyzing the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate. The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

42184 Da

Subcellular Location

Mitochondrion.

Prediction Reactivity

Monkey

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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