Anti-CENPC1 Antibody
Boster Bio Anti-CENPC1 Antibody catalog # A06766. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Centromere protein C; CENP-C; Centromere autoantigen C; Centromere protein C 1; CENP-C 1; Interphase centromere complex protein 7; CENPC; CENPC1, ICEN7
Gene Name
CENPC
UniProt
Q03188
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human CENPC (NP_001803.2) .
Clonality
Polyclonal
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPC recruits DNA methylation and DNMT3B to both centromeric and pericentromeric satellite repeats and regulates the histone code in these regions.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
106834 MW
Applications Notes
WB: 1:500-1:2000
Gene Name Synonym
Centromere protein C
Subcellular Location
Nucleus
Protein Name
Centromere protein C
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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