Puromycin HCl
Translation inhibitor
Product Specifications
Background
Puromycin is an antibiotic that is a protein synthesis inhibitor that causes premature chain termination during translation taking place in the ribosome. Part of the molecule resembles the 3' end of the tRNA. It enters the A site and transfers to the growing chain, causing the premature release. It is not selective for either prokaryotes or eukaryotes.
CAS Number
58-58-2
Product Name Alternative
3'-Deoxy-N, N-dimethyl-3'-[ (O-methyl-L-tyrosyl) amino]adenosine
UNSPSC
41116105
Type
Inhibitor
Source
Synthetic
Field of Research
Cancer | Apoptosis
Purity
>98% (TLC; HPLC) ; NMR (Conforms)
Weight
0.25
Format
Off-white powder
Solubility
May be dissolved in DMSO (50 mg/ml); or water (50 mg/ml)
Molecular Formula
C22H29N7O5•2HCl
Molecular Weight
544.43
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Azzam and Algranati. (1973) Proc Natl Acad Sci. 70: 3866.
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