Anti-Polyhomeotic-like protein 1 PHC1 Antibody
Boster Bio Anti-Polyhomeotic-like protein 1 PHC1 Antibody catalog # A06437. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Polyhomeotic-like protein 1; hPH1; Early development regulatory protein 1; PHC1; EDR1, PH1
Gene Name
PHC1
UniProt
P78364
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human PHC1 (NP_004417.2) .
Clonality
Polyclonal
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Required for proper control of cellular levels of GMNN expression.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
105534 MW
Applications Notes
WB: 1:500-1:2000
Gene Name Synonym
Polyhomeotic-like protein 1
Subcellular Location
Nucleus
Protein Name
Polyhomeotic-like protein 1
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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