2-Hydroxy Ibuprofen

2-Hydroxy Ibuprofen is a metabolite of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively.

Product Specifications

CAS Number

[51146-55-5]

Product Name Alternative

(±) -2-Hydroxy Ibuprofen

UNSPSC

12352005

Hazard Statement

H315-H319-H335

Target

COX

Type

Natural Products

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/2-hydroxy-ibuprofen.html

Solubility

10 mM in DMSO

Smiles

O=C(O)C(C)C1=CC=C(CC(C)(O)C)C=C1

Molecular Formula

C13H18O3

Molecular Weight

222.28

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362-P403+P233-P405-P501

References & Citations

[1]Noreen Y, et al. Development of a radiochemical cyclooxygenase-1 and -2 in vitro assay for identification of natural products as inhibitors of prostaglandin biosynthesis. J Nat Prod. 1998 Jan;61 (1) :2-7.