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2-Hydroxy Ibuprofen

Product Specifications

UNSPSC Description

2-Hydroxy Ibuprofen is a metabolite of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively.

Target Antigen

COX

Type

Natural Products

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/2-hydroxy-ibuprofen.html

Solubility

10 mM in DMSO

Smiles

O=C(O)C(C)C1=CC=C(CC(C)(O)C)C=C1

Molecular Weight

222.28

References & Citations

[1]Noreen Y, et al. Development of a radiochemical cyclooxygenase-1 and -2 in vitro assay for identification of natural products as inhibitors of prostaglandin biosynthesis. J Nat Prod. 1998 Jan;61(1):2-7.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-126121/2-Hydroxy-Ibuprofen-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-126121/

Clinical Information

No Development Reported

CAS Number

51146-55-5

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