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Anti-RGS10 Antibody

Boster Bio Anti-RGS10 Antibody catalog # A05197. Tested in WB, IHC applications. This antibody reacts with Human.

Product Specifications

Synonyms

Regulator of G-protein signaling 10; RGS10; RGS10

Gene Name

RGS10

UniProt

O43665

Host

Rabbit

Reactivity

Human

Immunogen

Synthetic peptide, corresponding to amino acids 357-402 of Human RGS10.

Clonality

Polyclonal

Applications

WB, IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Regulates G protein-coupled receptor signaling cascades, including signaling downstream of the muscarinic acetylcholine receptor CHRM2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:8774883, PubMed:10608901, PubMed:9353196, PubMed:11443111, PubMed:18434541) . Modulates the activity of potassium channels that are activated in response to CHRM2 signaling (PubMed:11443111) . Activity on GNAZ is inhibited by palmitoylation of the G-protein (PubMed:9353196) .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

20236 MW

Gene Name Synonym

Regulator of G-protein signaling 10

Subcellular Location

Cytoplasm, cytosol

Protein Name

Regulator of G-protein signaling 10

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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