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APTO-253

Product Specifications

CAS Number

916151-99-0

Synonyms

LOR-253, LT-253

SKU

C12350-5mg

Target

Myc

Applications

Apoptosis

Smiles

CC1=C (C2=NC3=C ([NH]2) C4=CC=CN=C4C5=C3C=CC=N5) C6=C ([NH]1) C=CC (=C6) F

Molecular Formula

C22H14FN5

Additionnal Information

APTO-253 (LOR-253, LT-253) inhibits c-Myc expression and selectively induces CDKN1A (p21), promotes G0-G1 cell-cycle arrest, and triggers apoptosis in acute myeloid leukemia (AML) cells. APTO-253 is also an inducer of KLF4 (Krüppel-like factor 4) .

Storage Conditions

3 years -20°C powder

Available Sizes

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