Anti-Lymphoid-specific helicase HELLS Antibody
Boster Bio Anti-Lymphoid-specific helicase HELLS Antibody catalog # A04702. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Lymphoid-specific helicase;3.6.4.-; Proliferation-associated SNF2-like protein; SWI/SNF2-related matrix-associated actin-dependent regulator of chromatin subfamily A member 6; HELLS
Gene Name
HELLS
UniProt
Q9NRZ9
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant full length Human HELLS.
Clonality
Polyclonal
Tissue Specificity
Highly expressed in proliferative tissues such as adult thymus and testis, and expressed at lower levels in uterus, small intestine, colon, and peripheral blood mononuclear cells. Also expressed in neoplastic cell lines including those derived from myeloid and lymphoid leukemias.
Applications
WB, IHC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Plays an essential role in normal development and survival. Involved in regulation of the expansion or survival of lymphoid cells. Required for de novo or maintenance DNA methylation. May control silencing of the imprinted CDKN1C gene through DNA methylation. May play a role in formation and organization of heterochromatin, implying a functional role in the regulation of transcription and mitosis (By similarity) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
97074 MW
Gene Name Synonym
Lymphoid-specific helicase
Subcellular Location
Nucleus . Closely associated with pericentric heterochromatin. .
Protein Name
Lymphoid-specific helicase
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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