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Anti-CAC1S CACNA1S Antibody

Boster Bio Anti-CAC1S CACNA1S Antibody catalog # A03006. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Voltage-dependent L-type calcium channel subunit alpha-1S; Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle; Voltage-gated calcium channel subunit alpha Cav1.1; CACNA1S; CACH1, CACN1, CACNL1A3

Gene Name

CACNA1S

UniProt

Q13698

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human protein at AA range: 330-410

Clonality

Polyclonal

Tissue Specificity

Skeletal muscle specific.

Applications

WB, ELISA

Purification

CAC1S antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/mL

Form

Liquid

Function

Pore-forming, alpha-1S subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Calcium channels containing the alpha-1S subunit play an important role in excitation-contraction coupling in skeletal muscle via their interaction with RYR1, which triggers Ca (2+) release from the sarcplasmic reticulum and ultimately results in muscle contraction. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

212350 MW

Gene Name Synonym

Voltage-dependent L-type calcium channel subunit alpha-1S

Subcellular Location

Cell membrane, sarcolemma

Protein Name

Voltage-dependent L-type calcium channel subunit alpha-1S

Isotype

IgG

Contents

Liquid form in PBS containing 50% glycerol, and 0.02% sodium azide.

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