Anti-Cocaine esterase CES2 Antibody
Boster Bio Anti-Cocaine esterase CES2 Antibody catalog # A02868. Tested in WB, IHC applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
Cocaine esterase;3.1.1.84; Carboxylesterase 2; CE-2; hCE-2;3.1.1.1; Methylumbelliferyl-acetate deacetylase 2;3.1.1.56; CES2; ICE
Gene Name
CES2
UniProt
O00748
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthetic peptide, corresponding to amino acids 379-424 of Human CES2.
Clonality
Polyclonal
Tissue Specificity
Preferentially expressed in intestine with moderate expression in liver. Within the intestine, highest expression is found in small intestine with lower expression in colon and rectum.
Applications
WB, IHC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs (PubMed:9169443) . Shows high catalytic efficiency for hydrolysis of cocaine, 4- methylumbelliferyl acetate, heroin and 6-monoacetylmorphine (PubMed:9169443) . Hydrolyzes aspirin, substrates with large alcohol group and small acyl group and endogenous lipids such as triacylglycerol (PubMed:28677105) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
61807 MW
Gene Name Synonym
Cocaine esterase
Subcellular Location
Endoplasmic reticulum lumen
Protein Name
Cocaine esterase
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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