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Anti-PDE5A Antibody

Boster Bio Anti-PDE5A Antibody catalog # A02490. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

CGMP-specific 3',5'-cyclic phosphodiesterase;3.1.4.35

Gene Name

PDE5A

UniProt

O76074

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human PDE5A (NP_001074.2) .

Clonality

Polyclonal

Tissue Specificity

Expressed in aortic smooth muscle cells, heart, placenta, skeletal muscle and pancreas and, to a much lesser extent, in brain, liver and lung.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'- GMP (PubMed:9714779, PubMed:15489334) . Specifically regulates nitric-oxide-generated cGMP (PubMed:15489334) .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

99985 MW

Applications Notes

WB: 1:500-1:2000

Gene Name Synonym

CGMP-specific 3',5'-cyclic phosphodiesterase

Protein Name

CGMP-specific 3',5'-cyclic phosphodiesterase

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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