Anti-PEX1 Antibody Picoband® HRP Conjugated

Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and ubiquitin-modified protein reader activity. Predicted to be involved in establishment of protein localization to peroxisome; microtubule-based peroxisome localization; and protein unfolding. Located in peroxisome. Used to study Zellweger syndrome. Human ortholog (s) of this gene implicated in Heimler syndrome 1; peroxisome biogenesis disorder 1A; and peroxisome biogenesis disorder 1B. Orthologous to human PEX1 (peroxisomal biogenesis factor 1) .

1. Collins, C. S., Gould, S. J. Identification of a common PEX1 mutation in Zellweger syndrome. Hum. Mutat. 14: 45-53, 1999. 2. Crane, D. I., Maxwell, M. A., Paton, B. C. PEX1 mutations in the Zellweger spectrum of the peroxisome biogenesis disorders. Hum. Mutat. 26: 167-175, 2005. 3. Gartner, J., Moser, H., Valle, D. Mutations in the 70K peroxisomal membrane protein gene in Zellweger syndrome. Nature Genet. 1: 16-23, 1992.