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Anti-Histone H1.2 Monoclonal Antibody

Boster Bio Anti-Histone H1.2 Monoclonal Antibody catalog # M06243. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Histone deacetylase 11; HD11;3.5.1.98; HDAC11

Gene Name

HIST1H1C

Gene ID

3006

UniProt

P16403

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Histone H1.2

Clonality

Monoclonal

Clone

Clone: AEDF-8

Tissue Specificity

Weakly expressed in most tissues. Strongly expressed in brain, heart, skeletal muscle, kidney and testis.

Applications

WB, IHC, ICC, IF

Field of Research

2339, DNA/RNA, DNA Damage & Repair, DNA Damage Response, Epigenetics and Nuclear Signaling, Histones

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) . Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

39183 MW

Observed Molecular Weight

116 kDa

Gene Name Synonym

Histone deacetylase 11

Subcellular Location

Nucleus. Predominantly nuclear.

Protein Name

T-cell surface glycoprotein CD3 zeta chain

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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