Anti-Sprouty 2 SPRY2 Monoclonal Antibody
Selected Variant
M02089
Size: 100 µL/Vial
Boster Bio Anti-Sprouty 2 SPRY2 Monoclonal Antibody catalog # M02089. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Rat.
Product Specifications
Synonyms
Junctional adhesion molecule A; JAM-A; Junctional adhesion molecule 1; JAM-1; Platelet F11 receptor; Platelet adhesion molecule 1; PAM-1; CD321; F11R; JAM1, JCAM; UNQ264/PRO301
Gene Name
SPRY2
Gene ID
10253
UniProt
O43597
Host
Rabbit
Reactivity
Human, Rat
Immunogen
A synthesized peptide derived from human Sprouty 2 May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis.
Clonality
Monoclonal
Clone
Clone: AFOH-19
Tissue Specificity
Predominantly in urogenital tissues.
Applications
WB, IHC, ICC, IF, IP
Field of Research
Cardiovascular, Neurology Process, Neuroscience, Signaling Pathways, Stem Cells, Neural Signal Transduction, Cytoplasmic, Angiogenesis, Surface Molecules, TGF Beta, Mesenchymal Stem Cells
Purification
Affinity-chromatography
Concentration
0.5mg/ml
Form
Liquid
Function
Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity) . Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus. .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
32583 MW
Observed Molecular Weight
38 kDa
Gene Name Synonym
Junctional adhesion molecule A
Subcellular Location
Cell junction, tight junction . Cell membrane ; Single-pass type I membrane protein . Localized at tight junctions of both epithelial and endothelial cells.
Protein Name
Lysosome-associated membrane glycoprotein 2 (Lamp2)
Isotype
Rabbit IgG
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
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