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Anti-NUMB Rabbit Monoclonal Antibody

Boster Bio Anti-NUMB Rabbit Monoclonal Antibody catalog # M01206. Tested in WB application. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Protein numb homolog; h-Numb; Protein S171; NUMB

Gene Name

NUMB

Gene ID

8650

UniProt

P49757

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human NUMB

Clonality

Monoclonal

Clone

Clone: AOGI-14

Tissue Specificity

Detected in platelets (at protein level) . Expressed by a variety of hematopoietic and epithelial cells. .

Applications

WB

Field of Research

Cytoplasmic, Neurogenesis, Neurology Process, Neuroscience, Signaling Pathways, Stem Cells

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

70804 MW

Observed Molecular Weight

17 kDa

Gene Name Synonym

Protein numb homolog

Subcellular Location

Membrane; Peripheral membrane protein.

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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