CP681301
Product Specifications
CAS Number
865317-32-4
Target
Others|||DNA/RNA Synthesis|||CDK
Related Pathways
Cell Cycle/Checkpoint|||DNA Damage/DNA Repair|||Others
Bioactivity
CP681301 is a potent inhibitor of CDK5 with antiproliferative activity. CP681301 exhibits anti-tumor activity in Drosophila. CP681301 decreases the expression of CD133, OLIG2, SOX2, KI67, pCDK5 protein level in Glioma stem cells (GSCs) . CP681301 reduces self-renewal in mouse glioma xenografts [1].
Smiles
CN(C)c1ccc(CC(=O)Nc2cc([nH]n2)C2CCC2)cc1
Molecular Formula
C17H22N4O
Molecular Weight
298.38
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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