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Anti-PLD5 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Phospholipase D family, member 5 is a protein that in humans is encoded by the PLD5 gene. Inactive phospholipase D5 (PLD5) is a variant of the phospholipase D enzyme family that lacks catalytic activity due to mutations or alterations in critical amino acid residues. Despite its inactivity, PLD5 is believed to contribute to cellular processes such as lipid metabolism and membrane dynamics, highlighting its potential regulatory roles in cellular signaling pathways.

Gene Name

PLD5

Gene ID

200150

UniProt

Q8N7P1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

E.coli-derived human PLD5 recombinant protein (Position: K247-K517) . Human PLD5 shares 95.9% amino acid (aa) sequence identity with mouse PLD5.

Clonality

Polyclonal

Applications

Flow Cytometry

Purification

Immunogen affinity purified.

Form

Liquid

References & Citations

1. Liu, J., Li, J., Ma, Y., Xu, C., Wang, Y., & He, Y. (2021) . MicroRNA miR-145-5p inhibits Phospholipase D 5 (PLD5) to downregulate cell proliferation and metastasis to mitigate prostate cancer. Bioengineered, 12 (1), 3240-3251. 2. Anney, R., Klei, L., Pinto, D., Regan, R., Conroy, J., Magalhaes, T. R., ... & Gill, M. (2010) . A genome-wide scan for common alleles affecting risk for autism. Human molecular genetics, 19 (20), 4072-4082. 3. McCauley, J. L., Zuvich, R. L., Bradford, Y., Kenealy, S. J., Schnetz-Boutaud, N., Gregory, S. G., ... & Haines, J. L. (2009) . Follow-up examination of linkage and association to chromosome 1q43 in multiple sclerosis. Genes & Immunity, 10 (7), 624-630.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

61,51,38,54 kDa

Applications Notes

6

Isotype

IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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