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Anti-IMP4 Antibody Picoband® Fluoro594 Conjugated

Product Specifications

Background

U3 small nucleolar ribonucleoprotein protein IMP4 is a protein that in humans is encoded by the IMP4 gene. The protein encoded by this gene, along with IMP3 and MPP10, is part of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP) complex. This complex is necessary for the early cleavage steps of pre-18S ribosomal RNA processing. Several transcript variants encoding different isoforms have been found for this gene.

Synonyms

70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70 (S6K) alpha antibody, p70 (S6K) -alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody

Gene Name

IMP4

Gene ID

92856

UniProt

Q96G21

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross reactivity with other proteins.

Immunogen

E.coli-derived human PCF11 recombinant protein (Position: N1214-V1555) .

Clonality

Polyclonal

Tissue Specificity

Expressed in all tissues.

Applications

Flow Cytometry

Field of Research

Signal Transduction, Signaling Pathway, Small G Proteins

Purification

Immunogen affinity purified.

Form

Liquid

Function

Downstream effector of TOR signaling pathway involved in osmotic stress response. Could be involved in the control of plant growth and development. Phosphorylates the ribosomal proteins P14, P16 and S6. Functions as a repressor of cell proliferation and required for maintenance of chromosome stability and ploidy levels through the RBR1-E2F pathway.

References & Citations

1. Granneman, S., Gallagher, J. E. G., Vogelzangs, J., Horstman, W., van Venrooij, W. J., Baserga, S. J., Pruijn, G. J. M. The human Imp3 and Imp4 proteins form a ternary complex with hMpp10, which only interacts with the U3 snoRNA in 60-80S ribonucleoprotein complexes. Nucleic Acids Res. 31: 1877-1887, 2003.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

52588 MW

Applications Notes

6

Gene Name Synonym

Serine/threonine-protein kinase AtPK1/AtPK6

Subcellular Location

Cytoplasm. Nucleus.

Protein Name

Serine/threonine-protein kinase AtPK1/AtPK6

Isotype

IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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