Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-TSC22D1 Antibody Picoband®

Boster Bio Anti-TSC22D1 Antibody Picoband® catalog # A06397-2. Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

TSC22 domain family protein 1 is a protein that in humans is encoded by the TSC22D1 gene. This gene encodes a member of the TSC22 domain family of leucine zipper transcription factors. The encoded protein is stimulated by transforming growth factor beta, and regulates the transcription of multiple genes including C-type natriuretic peptide. The encoded protein may play a critical role in tumor suppression through the induction of cancer cell apoptosis, and a single nucleotide polymorphism in the promoter of this gene has been associated with diabetic nephropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Synonyms

Rho-related GTP-binding protein Rho6; Rho family GTPase 1; Rnd1; RND1; RHO6

Gene Name

TSC22D1

Gene ID

8848

UniProt

Q15714

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human TSC22D1 recombinant protein (Position: N179-Q926) .

Clonality

Polyclonal

Tissue Specificity

Mostly expressed in brain and liver.

Applications

WB, Flow Cytometry, ELISA

Field of Research

Actin Assembly, Actin, etc., Cytoskeleton, Cytoskeleton/ECM, G Protein Signaling, Microfilaments, Ras Family, Signal Transduction, Signaling Pathway, Small G Proteins

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Lacks intrinsic GTPase activity. Has a low affinity for GDP, and constitutively binds GTP. Controls rearrangements of the actin cytoskeleton. Induces the Rac-dependent neuritic process formation in part by disruption of the cortical actin filaments. Causes the formation of many neuritic processes from the cell body with disruption of the cortical actin filaments. .

References & Citations

1. Jay, P., Ji, J. W., Marsollier, C., Taviaux, S., Berge-Lefranc, J.-L., Berta, P. Cloning of the human homologue of the TGF-beta-stimulated clone 22 gene. Biochem. Biophys. Res. Commun. 222: 821-826, 1996. 2. Kester, H. A., Blanchetot, C., den Hertog, J., van der Saag, P. T., van der Burg, B. Transforming growth factor-beta-stimulated clone-22 is a member of a family of leucine zipper proteins that can homo- and heterodimerize and has transcriptional repressor activity. J. Biol. Chem. 274: 27439-27447, 1999. 3. Ohta, S., Shimekake, Y., Nagata, K. Molecular cloning and characterization of a transcription factor for the C-type natriuretic peptide gene promoter. Europ. J. Biochem. 242: 460-466, 1996.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

26056 MW

Observed Molecular Weight

140-150 kDa

Applications Notes

6

Gene Name Synonym

Rho-related GTP-binding protein Rho6

Subcellular Location

Cell membrane ; Lipid-anchor ; Cytoplasmic side . Cytoplasm, cytoskeleton .

Protein Name

AP-2 complex subunit mu

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Rabbit anti-Schizosaccharomyces pombe (strain 972/24843)(Fission yeast) TAF9 Polyclonal Antibody
MBS7187572 Inquire

Rabbit anti-Schizosaccharomyces pombe (strain 972/24843)(Fission yeast) TAF9 Polyclonal Antibody

Ask
View Details
Tremelimumab Biosimilar - Research Grade
ICH5184-5mg 5 mg

Tremelimumab Biosimilar - Research Grade

Ask
View Details
Malotilate 5mg
A10552-5 5 mg

Malotilate 5mg

Ask
View Details
Recombinant Narcissus pseudonarcissus Histone H3
MBS1138964-01 0.05 mg (E-Coli)

Recombinant Narcissus pseudonarcissus Histone H3

Ask
View Details
Recombinant Narcissus pseudonarcissus Histone H3
MBS1138964-02 0.2 mg (E-Coli)

Recombinant Narcissus pseudonarcissus Histone H3

Ask
View Details
Recombinant Narcissus pseudonarcissus Histone H3
MBS1138964-03 0.5 mg (E-Coli)

Recombinant Narcissus pseudonarcissus Histone H3

Ask
View Details