SRPK1 Recombinant Rabbit Monoclonal Antibody [PSH08-26]
Serine/arginine-Rich Splicing Factor (SRSF) protein kinase-1 SRPK1 is an enzyme that in humans is encoded by the SRPK1 gene. This gene encodes a serine/arginine protein kinase specific for the SR (serine/arginine-rich domain) family of splicing factors. The protein localizes to the nucleus and the cytoplasm. It is thought to play a role in regulation of both constitutive and alternative splicing by regulating intracellular localization of splicing factors. A second alternatively spliced transcript variant for this gene has been described, but its full length nature has not been determined. SRPK1 enables angiogenesis, which is regulated by VEGF, which either initiates or inhibits vessel formation depending on alternative splicing.
Product Specifications
Product Name Alternative
Abbreviation
SRSF protein kinase 1, EC:2.7.11.1, SFRS protein kinase 1, Serine/arginine-rich protein-specific kinase 1 (SR-protein-specific kinase 1), SRPK1
Swiss Prot
Q96SB4 Human, O70551 Mouse,
Cellular Locus
Cytoplasm, Nucleus, nucleoplasm, Nucleus speckle, Chromosome.
Host
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Recombinant protein within human SRPK1 aa 251-500.
Isotype
IgG
Clone
PSH08-26
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IHC-P, IF-Tissue, FC, IP
Positive Control
Concentration
1 mg/mL
Dilution
WB: 1:5,000 ;IF-Cell: 1:500 ;IHC-P: 1:200-1:1,000 ;IF-Tissue: 1:200 ;FC: 1:1,000 ;IP: 1-2μg/sample
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 74 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
CAS Number
9000-83-3
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