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Anti-CD64/FCGR1A Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

High affinity immunoglobulin gamma Fc receptor I is a protein that in humans is encoded by the FCGR1A gene. It is mapped to 1q21.2. This gene encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1.

Synonyms

High affinity immunoglobulin gamma Fc receptor I; IgG Fc receptor I; Fc-gamma RI; FcRI; Fc-gamma RIA; FcgammaRIa; CD64; FCGR1A; FCG1; FCGR1; IGFR1

Gene Name

FCGR1A

Gene ID

2209

UniProt

P12314

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human CD64/FCGR1A recombinant protein (Position: A191-D254) .

Clonality

Polyclonal

Tissue Specificity

Monocyte/macrophage specific.

Applications

Flow Cytometry

Field of Research

Immunoglobulins, Immunology, Innate Immunity

Purification

Immunogen affinity purified.

Form

Liquid

Function

High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses.

References & Citations

1. Entrez Gene: FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) . 2. Maresco DL, Blue LE, Culley LL, Kimberly RP, Anderson CL, Theil KS (November 1998) . Localization of FCGR1 encoding Fcgamma receptor class I in primates: molecular evidence for two pericentric inversions during the evolution of human chromosome 1. Cytogenetics and Cell Genetics. 82 (1-2) : 71–4. 3. van de Winkel JG, Ernst LK, Anderson CL, Chiu IM (Jul 1991) . Gene organization of the human high affinity receptor for IgG, Fc gamma RI (CD64) . Characterization and evidence for a second gene.The Journal of Biological Chemistry. 266 (20) : 13449–55.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

38779 MW

Applications Notes

6

Gene Name Synonym

Fc fragment of IgG receptor Ia

Subcellular Location

Cell membrane.

Protein Name

BAG family molecular chaperone regulator 1

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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