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Anti-Hepatitis B Virus Antibody Picoband®

Boster Bio Anti-Hepatitis B Virus Antibody Picoband® catalog # A30379. Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Hepatitis B virus, abbreviated HBV, is a species of the genus Orthohepadnavirus, which is likewise a part of the Hepadnaviridae family of viruses. This virus causes the disease hepatitis B. It consists of HBsAg, HBcAg (HBeAg is a splice variant), Hepatitis B virus DNA polymerase and HBx. Among these, HBsAg (also known as the Australia antigen) is the surface antigen of the hepatitis B virus (HBV) . It indicates current hepatitis B infection. The viral envelope of an enveloped virus has different surface proteins from the rest of the virus which act as antigens. These antigens are recognized by antibody proteins that bind specifically to one of these surface proteins.

Synonyms

Large S protein ; S

Gene Name

S

Gene ID

944569

UniProt

D2X4M3

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human Hepatitis B Virus.

Clonality

Polyclonal

Tissue Specificity

Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.

Applications

IHC, WB

Field of Research

Cell Biology, Cell Type Markers, Tags & Cell Markers

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Involved in cellular response to oxidative stress.

References & Citations

1. Magnius LO, Norder H (1995) . Subtypes, genotypes and molecular epidemiology of the hepatitis B virus as reflected by sequence variability of the S-gene. Intervirology. 38 (1–2) : 24–34. 2. Rysgaard, Carolyn D; Morris, Cory S; Drees, Denny; Bebber, Tami; Davis, Scott R; Kulhavy, Jeff; Krasowski, Matthew D (2012) . Positive hepatitis B surface antigen tests due to recent vaccination: a persistent problem. BMC Clinical Pathology. 12 (1) : 15. doi:10.1186/1472-6890-12-15. Retrieved11 March 2014.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

6374 MW

Observed Molecular Weight

6 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Long surface protein; PreS1; L protein; LHBs; large S protein; pre-S1/pre-S2/S regions; L glycoprotein; L-HBsAG; LHBs

Subcellular Location

Secreted.

Protein Name

Large S protein

Isotype

Rabbit IgG

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

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