Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-TACC1 Antibody Picoband®

Boster Bio Anti-TACC1 Antibody Picoband® catalog # A04196. Tested in WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Transforming acidic coiled-coil-containing protein 1?is a?protein?that in humans is encoded by the?TACC1?gene. This locus may represent a breast cancer candidate gene. It is located close to FGFR1 on a region of chromosome 8 that is amplified in some breast cancers. Three transcript variants encoding different isoforms have been found for this gene.

Synonyms

Transforming acidic coiled-coil-containing protein 1; Gastric cancer antigen Ga55; Taxin-1; TACC1; KIAA1103

Gene Name

TACC1

Gene ID

6867

UniProt

O75410

Host

Rabbit

Reactivity

Human, Mouse

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human TACC1, different from the related mouse sequence by fourteen amino acids.

Clonality

Polyclonal

Tissue Specificity

Isoform 1, isoform 3 and isoform 5 are ubiquitous. Isoform 2 is strongly expressed in the brain, weakly detectable in lung and colon, and overexpressed in gastric cancer. Isoform 4 is not detected in normal tissues, but strong expression was found in gastric cancer tissues. Down-regulated in a subset of cases of breast cancer. .

Applications

WB

Field of Research

Cell Biology, Cell Cycle, Cell Differentiation, Epigenetics and Nuclear Signaling

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Likely involved in the processes that promote cell division prior to the formation of differentiated tissues.

References & Citations

1. Delaval B, Ferrand A, Conte N, Larroque C, Hernandez-Verdun D, Prigent C, Birnbaum D (Jun 2004) . Aurora B -TACC1 protein complex in cytokinesis.Oncogene. 23 (26) : 4516–22. 2. Conte N, Delaval B, Ginestier C, Ferrand A, Isnardon D, Larroque C, Prigent C, Séraphin B, Jacquemier J, Birnbaum D (Nov 2003) . TACC1-chTOG-Aurora A protein complex in breast cancer. Oncogene. 22 (50) : 8102–16.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

87794 MW

Observed Molecular Weight

100 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Transforming acidic coiled-coil-containing protein 1

Subcellular Location

Cytoplasm . Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Midbody . Nucleus during interphase. Weakly concentrated at centrosomes during mitosis and colocalizes with AURKC at the midbody during cytokinesis. .

Protein Name

Transforming acidic coiled-coil-containing protein 1

Isotype

Rabbit IgG

Contents

243

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

STX3 Recombinant Antibody, AbBy Fluor™ 555 Conjugated
bsm-61956R-BF555-01 20 µL

STX3 Recombinant Antibody, AbBy Fluor™ 555 Conjugated

Ask
View Details
STX3 Recombinant Antibody, AbBy Fluor™ 555 Conjugated
bsm-61956R-BF555-02 100 µL

STX3 Recombinant Antibody, AbBy Fluor™ 555 Conjugated

Ask
View Details
Bovine Protein FAM134B (FAM134B) ELISA Kit
MBS9921646-01 48 Well

Bovine Protein FAM134B (FAM134B) ELISA Kit

Ask
View Details
Bovine Protein FAM134B (FAM134B) ELISA Kit
MBS9921646-02 96 Well

Bovine Protein FAM134B (FAM134B) ELISA Kit

Ask
View Details
Bovine Protein FAM134B (FAM134B) ELISA Kit
MBS9921646-03 5x 96 Well

Bovine Protein FAM134B (FAM134B) ELISA Kit

Ask
View Details
Bovine Protein FAM134B (FAM134B) ELISA Kit
MBS9921646-04 10x 96 Well

Bovine Protein FAM134B (FAM134B) ELISA Kit

Ask
View Details