What is the catalog number for Anti-PIGR Antibody Picoband®?

The catalog number for Anti-PIGR Antibody Picoband® is PB9776.

What sizes are available for Anti-PIGR Antibody Picoband®?

Anti-PIGR Antibody Picoband® is available in the following size(s): 100 µg/Vial.

Is Anti-PIGR Antibody Picoband® in stock?

Anti-PIGR Antibody Picoband® is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-PIGR Antibody Picoband®?

The safety data sheet for Anti-PIGR Antibody Picoband® is available here: https://www.bosterbio.com/msds?sku=PB9776.

Anti-PIGR Antibody Picoband®

Boster Bio Anti-PIGR Antibody Picoband® catalog # PB9776. Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Polymeric immunoglobulin receptor is a protein that in humans is encoded by the PIGR gene. It is a Fc receptor which facilitates the secretion of the soluble polymeric isoforms of immunoglobulin A and immunoglobulin M. This gene is mapped to 1q31-q41. The encoded poly-Ig receptor binds polymeric immunoglobulin molecules at the basolateral surface of epithelial cells; the complex is then transported across the cell to be secreted at the apical surface. A significant association was found between immunoglobulin A nephropathy and several SNPs in this gene.

Synonyms

Polymeric immunoglobulin receptor; PIgR; Poly-Ig receptor; Hepatocellular carcinoma-associated protein TB6; Secretory component; PIGR

Gene Name

PIGR

Gene ID

5284

UniProt

P01833

Host

Rabbit

Reactivity

Human, Mouse

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human PIGR, different from the related rat sequence by eighteen amino acids.

Clonality

Polyclonal

Tissue Specificity

Widely expressed, with highest expression in liver and kidney.

Applications

Flow Cytometry, WB

Field of Research

Immunoglobulins, Immunology, Receptors

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

This receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment.

References & Citations

1. Entrez Gene: PIGR polymeric immunoglobulin receptor. 2. Hood L, Kronenberg M, Hunkapiller T (Feb 1985) . T cell antigen receptors and the immunoglobulin supergene family. Cell 40 (2) : 225–9. 3. Kaetzel CS (Aug 2005) . The polymeric immunoglobulin receptor: bridging innate and adaptive immune responses at mucosal surfaces. Immunological Reviews 206: 83–99.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

83284 MW

Observed Molecular Weight

83 kDa

Specificity

No cross reactivity with other proteins.

Applications Notes

Gene Name Synonym

Polymeric immunoglobulin receptor

Subcellular Location

Cell membrane; Single-pass type I membrane protein.

Protein Name

Polymeric immunoglobulin receptor

Isotype

Rabbit IgG

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

AM50159PU-T 20 µg

CD45 (PTPRC) (CD45RA) Mouse Monoclonal Antibody [Clone ID: SPM568]

View Details

362623 200 µL

COIL (Coilin, CLN80, P80-Coilin)

View Details

E311226 200 µL

MDFI Antibody

View Details

PH38352M5 20 µg

TIE1 (NM_005424) Human Recombinant Protein

View Details

484240 100 µL

KIF4A (Chromosome-Associated Kinesin KIF4A, Kinesin Family Member 4A)

View Details

E1406h 96 Tests

ELISA Kit For Lipopolysaccharide-binding protein

View Details

Anti-PIGR Antibody Picoband®

Product Specifications

Background

Synonyms

Gene Name

Gene ID

UniProt

Host

Reactivity

Cross Reactivity

Immunogen

Clonality

Tissue Specificity

Applications

Field of Research

Purification

Concentration

Form

Reconstitution

Function

References & Citations

Storage Conditions

Calculated Molecular Weight

Observed Molecular Weight

Specificity

Applications Notes

Gene Name Synonym

Subcellular Location

Protein Name

Isotype

Contents

Frequently Asked Questions

Explore Other Products

CD45 (PTPRC) (CD45RA) Mouse Monoclonal Antibody [Clone ID: SPM568]

COIL (Coilin, CLN80, P80-Coilin)

MDFI Antibody

TIE1 (NM_005424) Human Recombinant Protein

KIF4A (Chromosome-Associated Kinesin KIF4A, Kinesin Family Member 4A)

ELISA Kit For Lipopolysaccharide-binding protein