Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-Kallikrein 4/KLK4 Antibody Picoband® Fluoro647 Conjugated

Selected Variant

PB9260-Fluoro647

Size: 100 µg/Vial

Product Specifications

Background

Kallikrein-related peptidase 4, also known as PSTS or EMSP1, is a protein which in humans is encoded by the KLK4 gene. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. In particular, they may serve as biomarkers for both prostate cancer and breast cancer. It has been found that KLK4 is a proliferative factor with effects on gene expression and it may have a role in prostate cancer development and progression.

Synonyms

Kallikrein-4;3.4.21.-; Enamel matrix serine proteinase 1; Kallikrein-like protein 1; KLK-L1; Prostase; Serine protease 17; KLK4; EMSP1, PRSS17, PSTS

Gene Name

KLK4

Gene ID

9622

UniProt

Q9Y5K2

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human Kallikrein 4 recombinant protein (Position: I31-S254) .

Clonality

Polyclonal

Tissue Specificity

Expressed in prostate.

Applications

Flow Cytometry

Field of Research

Cancer, Cell Biology, Cytoskeleton/ECM, ECM Enzymes, Extracellular Matrix, Invasion/Microenvironment, Proteolysis/Ubiquitin, Proteolytic Enzymes, Signal Transduction

Purification

Immunogen affinity purified.

Form

Liquid

Function

Involved in enamel formation. .

References & Citations

1. Klokk, T. I., Kilander, A., Xi, Z., Waehre, H., Risberg, B., Danielson, H. E., Saatcioglu, F. Kallikrein 4 is a proliferative factor that is overexpressed in prostate cancer. Cancer Res. 67: 5221-5230, 2007. 2. Nelson PS, Gan L, Ferguson C, Moss P, Gelinas R, Hood L, Wang K (March 1999) . 3. Simmer JP, Fukae M, Tanabe T, Yamakoshi Y, Uchida T, Xue J, Margolis HC, Shimizu M, DeHart BC, Hu CC, Bartlett JD (June 2000) .

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

27032 MW

Specificity

No cross reactivity with other proteins.

Applications Notes

6

Gene Name Synonym

Kallikrein-4

Subcellular Location

Secreted.

Sequence Similarities

Belongs to the peptidase S1 family. Kallikrein subfamily.

Protein Name

Kallikrein-4

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Price

Sign In for Pricing

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Anti-NMDAR2C/GRIN2C Antibody Picoband® (Dylight550 Conjugate)
PB9374-Dylight550 100 µg

Anti-NMDAR2C/GRIN2C Antibody Picoband® (Dylight550 Conjugate)

Sign In for Pricing
View Details
MCAM (Melanoma Cell Adhesion Molecule) / MUC18 / CD146 (MCAM/3048), CF488A conjugate, 0.1mg/mL
BNC883048-500 1x 500 µL

MCAM (Melanoma Cell Adhesion Molecule) / MUC18 / CD146 (MCAM/3048), CF488A conjugate, 0.1mg/mL

Sign In for Pricing
View Details
Anti-AEBP2 Antibody Picoband®
PB9977 100 µg/Vial

Anti-AEBP2 Antibody Picoband®

Sign In for Pricing
View Details
DC-SIGN Recombinant Rabbit Monoclonal Antibody [JE31-24]
HA721382 100 µL

DC-SIGN Recombinant Rabbit Monoclonal Antibody [JE31-24]

Sign In for Pricing
View Details
Anti-GCSF Receptor/CSF3R Antibody Picoband® (Biotine Conjugate)
PA1906-Biotin 100 µg/Vial

Anti-GCSF Receptor/CSF3R Antibody Picoband® (Biotine Conjugate)

Sign In for Pricing
View Details
Anti-Parvin alpha/PARVA Antibody Picoband® (Cy3 Conjugate)
PB9555-Cy3 100 µg/Vial

Anti-Parvin alpha/PARVA Antibody Picoband® (Cy3 Conjugate)

Sign In for Pricing
View Details