BnO-PEG6-OH
BnO-PEG6-OH is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . BnO-PEG6-OH is also a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1][2].
Product Specifications
CAS Number
[24342-68-5]
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker; PROTAC Linkers
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; PROTAC
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/bno-peg6-oh.html
Purity
99.89
Solubility
10 mM in DMSO
Smiles
OCCOCCOCCOCCOCCOCCOCC1=CC=CC=C1
Molecular Formula
C19H32O7
Molecular Weight
372.45
Precautions
H302, H315, H319, H335
References & Citations
[1]Shaoyun Xiang, et al. Antibody drug conjugate, intermediate, preparation method, pharmaceutical composition and uses there. Patent WO2016197946A1.|[2]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Non-cleavable Linker; PEG Linkers
Available Sizes
Curated Selection
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