Recombinant Human TREM1 Protein (His Tag)
Product Specifications
Background
Triggering Receptor Expressed on Myeloid Cells 1 (TREM-1) is a transmembrane protein with a single Ig-like domain. TREM-1 associates with the adapter protein, DAP12, to deliver an activating signal. TREM-1 is expressed on blood neutrophils and monocytes, and the expression is up-regulated by bacterial LPS. TREM-1 is expressed at high levels on neutrophils of patients with microbial sepsis and in mice with a TREM-1/Fc fusion protein protected mice against LPS-induced shock. Human TREM-1 shares 42% sequence homology with mouse TREM-1.
Abbreviation
TREM1
Synonyms
CD354; TREM-1; TREM1; Triggering Receptor Expressed on Monocytes 1; Triggering Receptor Expressed on Myeloid Cells 1
UniProt
Q9NP99
Accession Number
Q9NP99
Expression System
HEK293 Cells
Tag
C-His
Sequence
Ala21-Arg200
Field of Research
Immunology
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/hxuah4
Product MSDS
https://789.bio/eb/48yrn9
Calculated Molecular Weight
21.3 kDa
Observed Molecular Weight
32-40 kDa
Species
Human
Available Sizes
Curated Selection
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