CRBN ligand-457
CRBN ligand-457 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-457 can be linked to a target protein ligand via a linker to form a PROTAC.
Product Specifications
CAS Number
[2925079-15-6]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
O=CC=1C=C2N=CN=CC2=C(C1)N3C(=O)NC(=O)CC3
Molecular Formula
C13H10N4O3
Molecular Weight
270.25
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
Curated Selection
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