Floxuridine-13C,15N2
Floxuridine-13C,15N2 (5-Fluorouracil 2'-deoxyriboside-13C,15N2) is the 13C- and 15N-labeled labeled Floxuridine (HY-B0097) . Floxuridine (5-Fluorouracil 2'-deoxyriboside) is a pyrimidine analog and known as an oncology antimetabolite. Floxuridine inhibits Poly (ADP-Ribose) polymerase and induces DNA damage by activating the ATM and ATR checkpoint signaling pathways in vitro. Floxuridine is a extreamly potent inhibitor for S. aureus infection and induces cell apoptosis[1][2]. Floxuridine has antiviral effects against HSV and CMV[3].
Product Specifications
Product Name Alternative
5-Fluorouracil 2'-deoxyriboside-13C,15N2
UNSPSC
12352005
Target
Apoptosis; Bacterial; CMV; DNA/RNA Synthesis; HSV; Isotope-Labeled Compounds; Nucleoside Antimetabolite/Analog
Related Pathways
Anti-infection; Apoptosis; Cell Cycle/DNA Damage; Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O[C@H]1C[C@@H](O[C@@H]1CO)[15N](C=C2F)[13C]([15NH]C2=O)=O
Molecular Formula
C8 13CH11F 15N2O5
Molecular Weight
249.17
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
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