PF 429242
Product Specifications
CAS Number
947303-87-9
Target
Fatty Acid Synthase|||Lipid|||Virus Protease|||NPC1L1
Related Pathways
Microbiology/Virology|||Metabolism|||Membrane transporter/Ion channel
Purity
0.9927
Bioactivity
PF-429242 is a competitive inhibitor of sterol regulatory element-binding protein (SREBP) site 1 protease (IC50 = 0.175 ?M) . It is selective for site 1 protease against a panel of serine proteases. PF-429242 inhibits rate of cholesterol synthesis in CHO cells (IC50 = 0.53 ?M) .
Smiles
N(C(=O)C1=CC=C(CN(CC)CC)C=C1)(CCC2=C(OC)C=CC=C2)[C@@H]3CCNC3
Molecular Formula
C25H35N3O2
Molecular Weight
409.56
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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