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Hydrouracil- (4-Chlorophenoxy) -O-C-COOH

Hydrouracil- (4-Chlorophenoxy) -O-C-COOH is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Hydrouracil- (4-Chlorophenoxy) -O-C-COOH can be linked to a target protein ligand via a linker to form a PROTAC.

Product Specifications

CAS Number

[2633725-30-9]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Ligands for E3 Ligase

Related Pathways

PROTAC

Field of Research

Cancer

Smiles

O=C(O)COC1=CC=C(Cl)C(=C1)N2C(=O)NC(=O)CC2

Molecular Formula

C12H11ClN2O5

Molecular Weight

298.68

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Cereblon

Curated Selection

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