PDE6B Polyclonal Antibody
This is a PDE6B Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Photon absorption triggers a signaling cascade in rod photoreceptors that activates cGMP phosphodiesterase (PDE), resulting in the rapid hydrolysis of cGMP, closure of cGMP-gated cation channels, and hyperpolarization of the cell. PDE is a peripheral membrane heterotrimeric enzyme made up of alpha, beta, and gamma subunits. This gene encodes the beta subunit. Mutations in this gene result in retinitis pigmentosa and autosomal dominant congenital stationary night blindness. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms
PDE6B, CSNB3, CSNBAD2, PDEB, RP40, rd1, GMP-PDEbeta
Gene ID
5158
Swiss Prot
P35913
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human PDE6B (NP_001138763.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
IHC 1:50-1:100
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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