Ticlopidine (hydrochloride) -d6
Ticlopidine hydrochloride-d6 is the deuterium labeled Ticlopidine hydrochloride. Ticlopidine (PCR 5332) hydrochloride, an antithrombotic proagent, acts as an allosteric, noncompetitive inhibitor of CD39 with the IC50 of 81.7 μM. Ticlopidine hydrochloride blocks several NTPDase isoenzymes with IC50s of 170 μM and 149 μM for NTPDase2 and NTPDase3, respectively[1]. Ticlopidine hydrochloride is an inhibitor of CYP2C19 human liver cytochrome. Ticlopidine hydrochloride inhibits CYP2C9 and CYP3A4 with IC50s of 26.0 and 32.3 μM, respectively[2][3].
Product Specifications
CAS Number
2985259-58-1
UNSPSC
12352005
Target
Cytochrome P450; Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; Others
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Smiles
ClC1=C(C([2H])=C(C([2H])=C1C([2H])(N2CC3=C(CC2)SC=C3)[2H])[2H])[2H].Cl
Molecular Formula
C14H9D6Cl2NS
Molecular Weight
306.28
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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