IMPDH-IN-2
IMPDH-IN-2 (compound 2) is an inhibitor of inosine monophosphate dehydrogenase (IMPDH) with IC50Values are 0.15 and 0.17 μM, respectively. IMPDH-IN-2 has antitumor activity[1].
Product Specifications
CAS Number
[31858-65-8]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
IMPDH
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
98.95
Smiles
CC1=C(C(C/C=C(CCC(O)=O)\C)=C(C2=C1COC2=O)O)O
Molecular Formula
C16H18O6
Molecular Weight
306.31
Precautions
H302, H315, H319, H335
References & Citations
[1] Mitsuhashi S, et al. Structure-activity relationships for inhibition of inosine monophosphate dehydrogenase and differentiation induction of K562 cells among the mycophenolic acid derivatives. Bioorg Med Chem. 2010 Nov 15;18 (22) :8106-11.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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