IN-RNA-IN-2
IN-RNA-IN-2 (compound 1a) is an inhibitor (IC50=70 nM) of the interaction between HIV-1 integrase and the viral RNA genome. IN-RNA-IN-2 exerts its anti-HIV activity by inhibiting the viral replication process[1].
Product Specifications
UNSPSC
12352005
Target
HIV; HIV Integrase
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/in-rna-in-2.html
Smiles
O=C(O)C(/C(O)=C/C(C1=CN(CC2=CC=C(F)C=C2)C3=C(C=C(C(/C=C(C(O)=O)\O)=O)C=C3)C1=O)=O)=O
Molecular Formula
C25H16FNO10
Molecular Weight
509.39
References & Citations
[1]Patacchini, et al. "Quinolinonyl Derivatives as Dual Inhibitors of the HIV-1 Integrase Catalytic Site and Integrase–RNA interactions." ACS Medicinal Chemistry Letters (2024) .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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