IN-RNA-IN-2
Product Specifications
UNSPSC Description
IN-RNA-IN-2 (compound 1a) is an inhibitor (IC50=70 nM) of the interaction between HIV-1 integrase and the viral RNA genome. IN-RNA-IN-2 exerts its anti-HIV activity by inhibiting the viral replication process[1].
Target Antigen
HIV; HIV Integrase
Type
Reference compound
Related Pathways
Anti-infection;Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/in-rna-in-2.html
Smiles
O=C(O)C(/C(O)=C/C(C1=CN(CC2=CC=C(F)C=C2)C3=C(C=C(C(/C=C(C(O)=O)\O)=O)C=C3)C1=O)=O)=O
Molecular Weight
509.39
References & Citations
[1]Patacchini, et al. "Quinolinonyl Derivatives as Dual Inhibitors of the HIV-1 Integrase Catalytic Site and Integrase–RNA interactions." ACS Medicinal Chemistry Letters (2024).
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-161945/IN-RNA-IN-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-161945/
Clinical Information
No Development Reported
Curated Selection
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