CRBN ligand-109
CRBN ligand-109 is a CRBN-type E3 ubiquitin ligase ligand that can be used to prepare PROTAC.
Product Specifications
CAS Number
[2758533-77-4]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
99.11
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C(C1=C(F)C=C(Br)C=C1F)CC2)NC2=O
Molecular Formula
C11H8BrF2NO2
Molecular Weight
304.09
Precautions
H302, H315, H319, H335
References & Citations
[1]Miletić N, et al. Workflow for E3 Ligase Ligand Validation for PROTAC Development. ACS Chem Biol. 2025 Feb 21;20 (2) :507-521.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
Available Sizes
Curated Selection
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