N- (7H-Purin-6-yl) acetamide

N- (7H-Purin-6-yl) acetamide (Compound 25) is a selective adenosine receptor (AdeR) agonist with a Ki value of 0.515 μM for the human adenosine receptor and a Ki value of 2.85 μM for the rat adenosine receptor. N- (7H-Purin-6-yl) acetamide is promising for research of adenosine receptor function, pain perception, inflammatory responses, and renal function[1].

Product Specifications

CAS Number

[6034-68-0]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Adenosine Receptor

Related Pathways

GPCR/G Protein

Field of Research

Inflammation/Immunology

Smiles

O=C(NC1=NC=NC=2N=CNC21)C

Molecular Formula

C7H7N5O

Molecular Weight

177.17

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Borrmann T, et al. Structure-activity relationships of adenine and deazaadenine derivatives as ligands for adenine receptors, a new purinergic receptor family. J Med Chem. 2009 Oct 8;52 (19) :5974-89.