Triisopropyl phosphate
Triisopropyl phosphate inhibits TFF1 and EGR3 gene expression, exhibits anti-estrogenic activity that inhibits Estradiol (HY-B0141) -induced MCF-7 cell proliferation with an EC50 of 341 μM. Triisopropyl phosphate inhibits the estrogen response element (ERE) -stimulated luciferase activity in MVLN cells with an EC50 of 900 μM[1].
Product Specifications
CAS Number
[513-02-0]
UNSPSC
12352211
Hazard Statement
H226, H315, H319, H335, H400
Target
Estrogen Receptor/ERR
Related Pathways
Vitamin D Related/Nuclear Receptor
Field of Research
Endocrinology
Purity
98.0
Smiles
O=P(OC(C)C)(OC(C)C)OC(C)C
Molecular Formula
C9H21O4P
Molecular Weight
224.23
Precautions
H226, H315, H319, H335, H400
References & Citations
[1]Li J, et al., Structure-Oriented Research on the Antiestrogenic Effect of Organophosphate Esters and the Potential Mechanism. Environ Sci Technol. 2020 Nov 17;54 (22) :14525-14534.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W106688/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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