Ac-RHKK (Ac) -AMC
Ac-RHKK (Ac) -AMC (Compound S1) is a fluorescent substrate for SITR6, that is based on p53 sequence. Ac-RHKK (Ac) -AMC mimics H3K56 deacetylation site and significantly increases the deacetylation signal with low signal-to-background ratio. Ac-RHKK (Ac) -AMC can be used for ageing and cancers research[1].
Product Specifications
CAS Number
1193634-36-4
UNSPSC
12352209
Target
Fluorescent Dye
Related Pathways
Others
Field of Research
Cancer; Metabolic Disease
Smiles
O=C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC1=CNC=N1)C(N[C@@H](CCCCN)C(N[C@@H](CCCCNC(C)=O)C(NC2=CC=C3C(OC(C=C3C)=O)=C2)=O)=O)=O)=O)C
Molecular Formula
C38H56N12O8
Molecular Weight
808.93
References & Citations
[1]Kokkonen P, et al. Studying SIRT6 regulation using H3K56 based substrate and small molecules. Eur J Pharm Sci. 2014 Oct 15;63:71-6.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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